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60MO Gut microbiota and efficacy of immune-checkpoint inhibitors (ICIs) in patients (pts) with advanced solid tumor: SCRUM-Japan MONSTAR-SCREEN

      MONSTAR-SCREEN is the nationwide cancer genome screening project of prospectively assessing gut microbiota and circulating tumor DNA in 2,000 pts with advanced solid tumor at 31 Japanese institutions. Recently, several studies have showed that gut microbiota modulates efficacy of ICIs across cancer types. Here we report an initial analysis of association between alpha diversity index (ADI) of fecal microbiome and efficacy of ICIs between Sep 2019 and Sep 2020.
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